Medical ultrasound has transformed diagnosis and management in all areas of clinical medicine. However, current ultrasound imaging has limited spatial resolution, depends on bulky devices and is highly user dependend. HybridEcho is an interdisciplinary group of engineers, computer scientists and physicians working on methods and technologies to resolve these issues.

With our research group we cover the complete area of medical ultrasound, from transducer development over signal design to advanced algorithms.

Transducer Design

Imaging & Signal Processing

Clinical Studies

Transducer Design

Imaging & Signal Processing

Clinical Studies

News
Completed Theses

Chronic liver diseases affect ~1.5 billion people worldwide and cause 3.5% of all deaths. Hepatic steatosis can progress to irreversible damage, making early detection crucial. Non-invasive assessment has been challenging, but quantitative ultrasound-based methods are gaining importance.

This study aimed to develop a quantitative ultrasound parameter to assess liver steatosis using transient elastography’s controlled attenuation parameter (CAP) as a reference. Raw ultrasound radiofrequency (RF) data from handheld devices were analyzed. The main hypothesis proposed a strong correlation between ultrasound attenuation recorded with a handheld linear transducer and CAP values.

Between November 2022 and March 2023, raw ultrasound data were collected from patients undergoing ultrasound and Fibroscan examinations using Clarius C3HD3 and L15HD3 transducers. Three-second recordings were processed using a Python script. A non-frequency-specific attenuation parameter (AP) and a frequency-specific AP were calculated via short-time Fast Fourier Transformation (stFFT). Pearson and Spearman correlation coefficients were determined, and Fishers-z tests compared correlations.

Data from 135 participants were analyzed. Pearson correlation coefficients between non-frequency-specific AP and CAP were 0.634 (C3) and 0.694 (L15). For frequency-specific AP, correlations were 0.693 (C3) and 0.712 (L15). The correlation between frequency-specific AP and CAP was not significantly higher than that of non-frequency-specific AP.

Strong correlations between ultrasound APs and CAP values suggest handheld ultrasound devices can quantify liver steatosis. However, frequency-specific APs require further investigation. Validation with MRI-PDFF is recommended.

Publications

Ultrasound Spectroscopy for the detection of inflammation in inflammatory bowel disease

Comparative Analysis of Mismatched Filtering Techniques: Cyclic vs. Non-Cyclic Approach

Learning and career trajectory

At HybridEcho, we offer a unique environment combining hands-on medical ultrasound research experience with structured academic and professional development. Guided by experienced physicians, our members gain insight into ultrasound examinations, while our technical experts introduce them to transducer fabrication and image reconstruction. Beyond research, we foster a vibrant community through group activities such as hikes, movie or game nights, and much more, creating a collaborative and inspiring atmosphere.

Find out more in the boxes below and reach out to moritz.herzog@tu-dresden.de if you’re interested!

Clinicum Digitale

Supported by the EKFZ for Digital Health and the local medtech cluster, we welcome 40 students every year for a springschool on medtech.

Read more at: https://digitalhealth.tu-dresden.de/career-education/students/clinicum-digitale/

Innovate-a-thon

In Cooperation with the MMS we annually host a MedTech hackathon with a price money of 1000 €.

Read more at: https://digitalhealth.tu-dresden.de/innovate-a-thon/

Thesis Concept
  • Structured support through biweekly Jour Fixe with your supervisor
  • Cross-connection through weekly meetings in your core team
  • Agile project management with Notion for efficient workflows
  • Publication opportunities: Present your research as a first author
  • Dedicated workspace on the university hospital premises
  • Industry collaborations with established companies and start-ups
Alumni and past thesis

Theses in Medicine:

  • Tina Gabriel
  • Jakob Schäfer

Theses in Transducer Design:

  • Marco Arnegger
  • Julian Kober
  • Luisa Recknagel
  • Tönnis Trittler
  • Julius Weber

Theses in Imaging & Signal Processing:

  • Edgar Dorausch
  • Cornelius Kühnöl
  • Franz Richter
  • Pascal Stöver

We have open positions for students (engineering, computer science and medicine) as SHK or for Bachelor-/Master-/Diplomathesis in the following areas:

  • Signal design for ultrasonic imaging, including support in the theoretical design and experimental validation.
  • Implementation of imaging algorithms in an FPGA.
  • AI-based analysis of ultrasonic raw data.
  • Usability studies of clinical ultrasound.
  • Simulation of acoustic metamaterials.

For all areas, we do not require specific knowledge beforehand, since most of the required skills are usually learned while working on the problem.

Who We Are

Group Leader

Moritz started his research career in anaesthesiology, developing new methods of ventilation and lung imaging. After starting his residency in gastroenterology in 2020, he started to build up the HybridEcho research group in 2020.

Richard is postdoctoral researcher and head of the “Health” group at
the Vodafone Chair (TU Dresden). He specializes in real-time imaging algorithms and innovative signal processing methods. After his diploma degree in Mechatronics and a Dr.-Ing. degree in Electrical Engineering, he worked as an Embedded Software Architect for renewable energies and as a Postdoc at IFW Dresden, focusing on photoacoustic-guided closed-loop control of microrobots.

Group Members

M. Sc. Edgar Dorausch

Lead scientist on image reconstruction

Edgar joined the HybridEcho group as a PhD student after finishing his master’s thesis on Fourier-based multistatic image reconstruction in 2022. Under the supervision of Prof. Gerhard Fettweis, he is responsible for the development of new algorithms for image reconstruction and data compression.

Dipl.-Ing. Julian Kober

Lead scientist on system integration

Julian joined the research group in 2022 after attending the “Clinicum Digitale”. In his diploma thesis he investigated the thermal behaviour of ultrasonic transducers during continuous broadband excitation. He is continuing his work as a PhD student, focusing on the hybrid integration of broadband ultrasound transducers.

Dipl.-Ing. Tönnis Trittler

Lead scientist on transducer manufacturing

Tönnis studied mechatronics at TU Dresden (2016 – 2022). For his diploma thesis, he joined the HybridEcho research group, investigating the micromachining of the piezoelectric material PMN-PT with ultrashort laser pulses. After graduation he started his PhD on the manufacturing of broadband ultrasound transducers.

M. Sc. Cornelius Kühnöl

Lead scientist on signal conditioning

Cornelius, a Microelectronics Master’s graduate from FAU Erlangen-Nürnberg, joined the project through a research internship. His passion for cutting-edge technology led him to complete a Master’s thesis on coded signals for MIMO ultrasound. As a Ph.D. candidate supervised by Prof. Fettweiß, Cornelius delves into System-on-Chip integration for advanced ultrasound imaging, along with FPGA implementations.

Dr. med. Antje Naas

Lead scientist on usability and image quality

Antje is a Medical Doctor at the University Hospital Dresden. She joined the HybridEcho team in 2023 to conduct multi-centered clinical studies for the analysis of RF Data under the patronage of Dr. Herzog and Prof. Hampe. Antje graduated 2016 at the TU Dresden in Medicine and worked in Switzerland before returning to the University Hospital Dresden in 2021.

M. Sc. Omid Chaghaneh

Lead scientist on quantitative ultrasound

Omid completed his M.Sc. in Computational Modeling and Simulation at TU Dresden in 2022. He joined the HybridEcho team in 2023 and is conducting research in Quantitative Ultrasound. His research is focusing on developing various mathematical models and analyzing ultrasonic signals with medical diagnosis purposes.

Dipl.-Ing. Pascal Stöver

Lead scientist on embedded software

After participating in the Clinicum Digitale in 2023, Pascal joined the HybridEcho team in 2024 to work on his diploma thesis. His research focused on implementing Edgar Dorausch’s Fourier-based image reconstruction algorithm on an adaptive compute acceleration platform. Pascal now continues as a scientific engineer, specializing in software prototyping for advanced ultrasound imaging systems.

Paul-Henry Koop

Lead scientist on clinical studies

Paul-Henry ….

Alexa Sieghardt

Lab Coordination

Alexa is a medical-technical assistant and has many years of professional experience in various medical fields and laboratories. She has been working at Dresden University Hospital since 2010 and since December 2024 she supported the HybridEcho team with the organization, clinical studies and laboratory experiments.

Student Members

Yannick Fuchs

SHK clinical studies

Yannick has been studying medicine at TU Dresden since 2023. After taking part in the Clinicum Digitale 2024, he joined the working group due to his interest in technical solutions for medicine. Currently, he is mainly working on algorithms for the automated analysis of raw ultrasound data.

Franz Richter

SHK image reconstruction

Franz studies computer science and joined the HybridEcho research group as a student assistant in November of 2022. He assists Edgar Dorausch in the process of optimizing Fourier-based image reconstruction algorithms. Being generally interested in low-level code optimization, Franz recently started writing his Bachelor thesis, where he investigates the real-time capabilities of a SoC for a specific imaging algorithm.

Mai Leonie Beckers

SHK biomediacal engeneering

Mai has been studying Biomedical Engineering at the TU Dresden since 2022. She joined the research group in 2024 as a student assistant and is currently focused on optimizing the testbed for measuring transducer design parameters.

Shamoil Ejaz

SHK signal architecture

Shamoil Ejaz is a master´s student in Nanoelectronic Systems at TU Dresden. In April 2024, he joined the HybridEcho group as a research assistant SHK. His research is centered on signal architecture and communication between ultrasound transducers, where he is contributing to advancements in this specialized field.

Lisa Schurck

SHK system integration

Lisa studies Biomedical Engeneering at the TU Dresden. She became part of the HybridEcho team in 2023. As a student assistant she works on improving the testbed an performs sound field measurements.

Thesis Students

Tina Gabriel

Thesis clinical studies

Tina Gabriel studies medicine at the Carl Gustav Carus Universitätsklinikum Dresden since 2019. In 2023, she became part of the HybridEcho Group for her medical thesis, where her research focuses on the acquisition and analysis of focal liver lesions through quantitative ultrasound techniques.

Johanna Pfeifer

Thesis clinical studies

Johanna Pfeifer studies medicine at the Carl Gustav Carus Universitätsklinikum Dresden since 2019. In April 2024, she became part of the HybridEcho Group for her medical thesis. She will support our team with the acquisition of data for the analysis of quantitative ultrasound techniques.

Jonas Petzsche

Thesis clinical studies

Jonas Petzsche has been studying medicine at the Carl Gustav Carus Universitätsklinikum Dresden since 2021. After participating in the Clinicum Digitale in March 2024, he joined the HybridEcho Group to work on his medical thesis. He will support our team in acquiring data for the analysis of quantitative ultrasound in patients with inflammatory bowel disease.

Erik Kaiser

Thesis economics

Erik Kaiser is studying industrial engineering at TU Dresden, majoring in finance and electrical engineering. He has been part of the HybridEcho team since January 2025 for his research and diploma thesis. He supports the team in their research on wearable ultrasound and future applications in wearables.

Tobias Gohlke

Thesis economics

Tobias joined the research group in 2024 after attending the “Clinicum Digitale.” In his diploma thesis, he is exploring the potential of wearable ultrasound patches for continuous monitoring of vital parameters. Studying Industrial Engineering at TU Dresden with a specialization in Biomedical Engineering, he combines his interdisciplinary expertise to advance the development and application of innovative ultrasound technologies.

Maximilian Brambach

Thesis economics

Maximilian Brambach studies Industrial Engineering at TU Dresden and joined HybridEcho in 2024 after attending Clinicum Digitale. For his research and diploma thesis he is investigating the ultrasound Market and the potential of HybridEcho in the Market.

Merit Städler

Thesis Hardware

Merit is studying Industrial Engineering at the TU Dresden. Following her participation in “Clinicum Digitale 2024,” she became a member of the HybridEcho team. As part of her thesis preparation, she is investigating methods to characterize CMUT behaviour. Her thesis will focus on evaluating the receiver sensitivity of CMUTs.

Former thesis Students

Jakob Schäfer

Thesis clinical studies

Jakob joined the HybridEcho team after attending the Clinicum Digitale for his medical thesis on the analysis of raw ultrasound data from the liver as part of his initial studies. In October 2024 he passed his thesis with summa cum laude and is now continuing to study medicine at the University of Halle.

Marco Arnegger

Marco studied mechatronics at the TU Dresden. After his engagement at Clinicum Digitale in 2023, he moved to HybridEcho for his thesis. He was dedicated to the characterization and simulation of CMUT behavior. He finished his thesis sucessfully in April 2024 an now works at Sunfire in Dresden.

Jacob Florentin Urban

Thesis hardware design

Jacob studied Industrial Design at TU Dresden and joined Hybrid Echo in 2024 after attending Clinicum Digitale. In his thesis he examined ways to improve the ergonomic properties of ultrasound probes in order to develop a new design. In December 2024 he sucessfully completed his Diploma thesis and will be a PhD-Student at the TU Munich from April 2025.

Patronage

Impressions
Cooperations
Fraunhofer IPMS | Marco Kircher

In collaboration with Fraunhofer IPMS, the HybridEcho Group investigates the potential of capacitive micromachined ultrasonic transducers (CMUTs) for ultrasonic applications. With many years of experience in ultrasound MEMS technology and its highly flexibel clean room processes Fraunhofer IPMS is supporting the special requirements of the HybridEcho development for super wideband signal use.

Fraunhofer IKTS | Susan Walter

The Fraunhofer IKTS site in Dresden‐Klotzsche has been working since many years in research and development of methods and systems for nondestructive evaluation. It offers methods, sensors and devices for different kinds of nondestructive testing and covers the entire value chain, all the way to prototype production. For special applications, Fraunhofer IKTS designs and manufactures customized ultrasonic probes and methods based on model calculations that can be adapted to different geometries, materials and other acoustic parameters in the best possible way. With this knowledge, it supports the HybridEcho group in developing highly effective and broadband piezoelectric ultrasound emitters.

Infineon Dresden

Infineon Dresden (IFD) is one of the largest and most modern semiconductor manufacturing and development sites. The main portfolio comprises discrete and smart power technologies, BiCMOS, embedded Flash, MEMS and Sensors. As partner in the HybridEcho Group IFD aims to develop MEMS-devices for medical applications.

Exelonix

Exelonix develops HW and SW for mobile communications systems especially in the area of the Internet of Things. The product portfolio comprises USB sticks with 4G/5G technologies, trackers, sensor nodes, and Bluetooth beacon enabled products, most connected to the cloud. In the HybridEcho Group Exelonix focuses on signal processing and interconnectivity.

Fraunhofer IPMS | Marco Kircher

In collaboration with Fraunhofer IPMS, the HybridEcho Group investigates the potential of capacitive micromachined ultrasonic transducers (CMUTs) for ultrasonic applications. With many years of experience in ultrasound MEMS technology and its highly flexibel clean room processes Fraunhofer IPMS is supporting the special requirements of the HybridEcho development for super wideband signal use.

Fraunhofer IKTS | Susan Walter

The Fraunhofer IKTS site in Dresden‐Klotzsche has been working since many years in research and development of methods and systems for nondestructive evaluation. It offers methods, sensors and devices for different kinds of nondestructive testing and covers the entire value chain, all the way to prototype production. For special applications, Fraunhofer IKTS designs and manufactures customized ultrasonic probes and methods based on model calculations that can be adapted to different geometries, materials and other acoustic parameters in the best possible way. With this knowledge, it supports the HybridEcho group in developing highly effective and broadband piezoelectric ultrasound emitters.

Infineon Dresden

Infineon Dresden (IFD) is one of the largest and most modern semiconductor manufacturing and development sites. The main portfolio comprises discrete and smart power technologies, BiCMOS, embedded Flash, MEMS and Sensors. As partner in the HybridEcho Group IFD aims to develop MEMS-devices for medical applications.

Exelonix

Exelonix develops HW and SW for mobile communications systems especially in the area of the Internet of Things. The product portfolio comprises USB sticks with 4G/5G technologies, trackers, sensor nodes, and Bluetooth beacon enabled products, most connected to the cloud. In the HybridEcho Group Exelonix focuses on signal processing and interconnectivity.

Contronix

more information coming soon

SITEC

SITEC is valued across the world as a partner and supplier of automated production systems and for series manufacturing of modules and components. Our strengths include the optimisation of technological se­quences and flexible reaction to the challenges of a dynamic market with ever-shorter product cycles. In the in-house application center, 14 different laser sources of different designs and wavelengths are available for technology development. Based on the highest quality and environmental standards, SITEC offers efficient production technologies and complete turnkey solutions Made in Germany.

WOLFRAM Designer und Ingenieure

WOLFRAM Designer und Ingenieure (WDI) offers user-centered engineering and design services. The interdisciplinary team of designers and engineers provides product development for the market entry of technical innovations. WDI supports the HybridEcho research group in the product development process:

  • product conception and product design
  • usability conception, user interface design and user experience
  • mechanical engineering, technology integration and prototyping
Heteromerge

HETEROMERGE is a StartUp company that offers complete multi-material solutions for 3D micro-printing to realize high-performant functional systems. Based on our multi-material print head, we provide automated in situ material exchange in two-photon 3D laser-printing. As partner in the HybridEcho group, we support the fabrication of novel ultrasonic transducer elements via micro-additive processes.

Contronix

More information coming soon

SITEC

SITEC is valued across the world as a partner and supplier of automated production systems and for series manufacturing of modules and components. Our strengths include the optimisation of technological se­quences and flexible reaction to the challenges of a dynamic market with ever-shorter product cycles. In the in-house application center, 14 different laser sources of different designs and wavelengths are available for technology development. Based on the highest quality and environmental standards, SITEC offers efficient production technologies and complete turnkey solutions Made in Germany.

WOLFRAM Designer und Ingenieure

WOLFRAM Designer und Ingenieure (WDI) offers user-centered engineering and design services. The interdisciplinary team of designers and engineers provides product development for the market entry of technical innovations. WDI supports the HybridEcho research group in the product development process:

  • product conception and product design
  • usability conception, user interface design and user experience
  • mechanical engineering, technology integration and prototyping
Heteromerge

HETEROMERGE is a StartUp company that offers complete multi-material solutions for 3D micro-printing to realize high-performant functional systems. Based on our multi-material print head, we provide automated in situ material exchange in two-photon 3D laser-printing. As partner in the HybridEcho group, we support the fabrication of novel ultrasonic transducer elements via micro-additive processes.

Funded by
Logo EKFZ
Logo BMBF Förderung
TUD Logo

HybridEcho is also part of the Cluster4Future SEMECO. The Free State of Saxony is additionally funding this project. HybridEcho complements the innovative pool of ideas in the cluster ecosystem.

Skip to content