Evidence-Based Implementation of Digital Health Solutions

The research group focuses on user-centered development, acceptance, implementation, and effectiveness of digital healthcare services.

Mission

The central mission of the research group, led by Dr. Madlen Scheibe and located at the Center for Evidence-based Healthcare, is the evidence-based translation and implementation of digital healthcare services into everyday healthcare.

It provides answers to the key question: What are predictive parameters for successful transfer of innovation into medical practice with the aim to successfully implement effective digital health innovation in the healthcare system and thus improve the health of individuals and the population?

Driving the Future of Digital Healthcare

The work of the research group addresses three interwoven key areas that are critical for the successful and sustainable implementation of digital healthcare services. However, these areas have not yet been sufficiently researched.  Our work aims to close this gap by generating the evidence needed for reliable and future-ready recommendations.

Implementing Core Outcomes Sets in Digital Health

In our research we address critical gaps in applying Core Outcome Sets (COS) to digital health interventions, exploring their validity, usability, and relevance in this rapidly evolving field. By aligning COS with the specific needs of digital tools, we can enhance patient-centeredness, evidence comparability and improve guideline development.

Shaping the Future of Digital Health Literacy

In our research we focus on digital health literacy as a key factor for equitable access, effective use, and positive outcomes in digital healthcare. By addressing the digital divide, evaluating the suitability of existing measurement tools, and developing targeted, participatory interventions, we aim to empower users and support the successful implementation of digital health solutions.

Timely Insights Through the Digital Health Panel

Our research group is establishing a regional Digital Health Panel to enable ongoing, up-to-date implementation research. Through regular surveys of a representative population sample, we generate vital insights into acceptance, usage, added value, and key drivers and barriers to the successful integration of digital healthcare solutions.

Dr. Madlen Scheibe

Dr. Madlen Scheibe has been driving research in digital health since 2012 and has led the Digital Health research division at the Center for Evidence-Based Healthcare (ZEGV) at the Dresden Medical Faculty and University Hospital since 2018. Her work centers on the acceptance, effectiveness, and implementation of digital health solutions.

She currently serves as the consortium lead of ImplementDiGA — Germany’s largest research project on the implementation and impact of DiGA. Dr. Scheibe also oversees the scientific evaluation of the Children’s Tele-Intensive Care Network Saxony, which was awarded the German Telemedicine Prize by the German Society for Telemedicine in 2025. She leads a sub-project within the BMBF-funded PATH project, investigating what enables patients to share their data with healthcare providers, researchers, and companies. Since 2024, she is heading the EKFZ research group “Evidence-Based Implementation of Digital Health Solutions”.

In 2023, Dr. Scheibe was named one of the Top 3 Digital Female Leaders in Health at the Digital Female Leader Award. She is a reviewer for several funding bodies and international journals as well as an active member of the Digital Health working group within the German Network for Health Services Research (DNVF).

Recent Publications

Sippli K, Deckert S, Schmitt J, Scheibe M (2025) Healthcare effects and evidence robustness of reimbursable digital health applications in Germany: A systematic review. npj Digit. Med (accepted)

Fesl S, Lang C, Schmitt J, et al. Factors influencing patients’ willingness to share their digital health data for primary and secondary use: A theory- and evidence-based overview of reviews. DIGITAL HEALTH. 2025;11. doi: 10.1177/20552076251340254.

Brückner, S., Sadare, O., Fesl, S. et al. Attitudes of healthcare professionals and researchers toward wearable and app derived patient generated health data. npj Digit. Med. 8, 186 (2025). https://doi.org/10.1038/s41746-025-01568-4

Mathiebe, J.; Müller, G.; Schmitt, J.; Brenner, S.; Winkler, S.; Schawohl, A.; Waurig, F.; Scheibe, M. How to Evaluate a Regional Telemedical Care Network Focusing on Critically Ill Children? Results from the Consensus-Based Development of an Evaluation Design. Children 2025, 12, 313. https://doi.org/10.3390/children12030313

Knapp A, Harst L, Hager S, Schmitt J, Scheibe M. Use of Patient-Reported Outcome Measures and Patient-Reported Experience Measures Within Evaluation Studies of Telemedicine Applications: Systematic Review, J Med Internet Res 2021;23(11):e30042, https://www.jmir.org/2021/11/e30042; DOI: 10.2196/30042

Digitale Gesundheitsinterventionen entwickeln, evaluieren und implementieren (Teil I) – Diskussionspapier der Arbeitsgruppe Digital Health des Deutschen Netzwerk Versorgungsforschung (DNVF); Sven Kernebeck, Madlen Scheibe, Monika Sinha, Florian Fischer, Andreas Knapp, Patrick Timpel, Lorenz Harst, Ulrich Reininghaus, Horst Christian Vollmar; Publication: Das Gesundheitswesen; Publisher: Georg Thieme Verlag KG; Nov 29, 2022

Digitale Gesundheitsinterventionen entwickeln, evaluieren und implementieren Teil II – Diskussionspapier der Arbeitsgruppe Digital Health des Deutschen Netzwerk Versorgungsforschung (DNVF); Sven Kernebeck, Madlen Scheibe, Monika Sinha, Florian Fischer, Andreas Knapp, Patrick Timpel, Lorenz Harst, Ulrich Reininghaus, Horst Christian Vollmar; Publication: Das Gesundheitswesen, Publisher: Georg Thieme Verlag KG, Nov 29, 2022

Contact

The research group is a cooperation of the Center for Evidence-Based Healthcare at the Dresden Medical Faculty and University Hospital and the Else Kröner Fresenius Center (EKFZ) for Digital Health.
Head of Research Group

Dr. Madlen Scheibe

Team member

Pauline Kaboth, M. Sc.

Team member

Franz Kappert, MPH

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