Digital transformation of healthcare through the implementation
of the Hospital-at-Home concept
Smart Home Care – Junior Research Group
A Collaborative Effort in Digital Health Innovation: The “Smart Home Care” research group represents a pioneering collaboration between the EFKZ for Digital Health in Dresden and the Hasso Plattner Institute (HPI) in Potsdam. Under the leadership of Dr. Anne Sophie Kubasch, who holds positions at both institutions, this initiative merges clinical expertise with digital engineering innovation to address the pressing challenges of modern healthcare.
Dr. med. Anne Sophie Kubasch
Our vision is to reshape healthcare through Smart Home Care by integrating advanced digital technologies and the Hospital-at-Home concept. By bringing personalized medical services directly to patients’ homes, we aim to improve recovery, enhance quality of life, and set new standards for innovative, patient-centered solutions.
Vision
The “Smart Home Care” junior research group at EKFZ focuses on the digital transformation of healthcare through the implementation of the Hospital-at-Home (HaH) concept. This innovative approach shifts hospital-grade medical care into the patient’s home environment by leveraging advanced digital technologies and mobile medical teams.
Mission
Our mission is to enhance healing processes, improve patients’ quality of life, and reduce the burden on healthcare systems. By driving innovation in healthcare, the group addresses pressing challenges in the German healthcare system, including an aging population and the need for patient-centered solutions that integrate seamlessly into existing care structures.
Hospital-at-Home: A Transformative Model for Germany
At the heart of this project is the Hospital-at-Home (HaH) model—an innovative concept particularly vital for addressing the healthcare demands of an aging population and tackling the high prevalence of long-term hospital stays in Germany. By delivering hospital-level care directly into patients’ homes, the HaH model offers a personalized, patient-centered alternative that improves outcomes while alleviating strain on healthcare facilities and resources.
The “Smart Home Care” group is dedicated to improve healthcare delivery through state-of-the-art digital tools. These include predictive analytics to enhance clinical decision-making, remote monitoring for continuous oversight, and seamless communication systems to strengthen connections between patients and their medical teams. Drawing on successful HaH programs in Israel, the United States, and Switzerland, the group is developing evidence-based solutions tailored to the unique needs of the German healthcare system.
Piloting Scalable Solutions at University Hospital Dresden
In collaboration with the University Hospital Carl Gustav Carus Dresden, the group is piloting clinical applications designed to create scalable, sustainable healthcare models for the future. By fostering interdisciplinary partnerships between EKFZ and HPI and leveraging new digital technologies, the “Smart Home Care” research group is setting new benchmarks for personalized, efficient, and effective healthcare.
Publications
Kubasch AS, Peterlin P, Cluzeau T, Götze KS, Sockel K, Teipel R, Jentzsch M, Attalah H, Sebert M, Chermat F, Gloaguen S, Puttrich, M, Kayser S, Schipp D, Giagounidis A, Tirado-Gonzalez I, Descot A, Van de Loosdrecht AA, Weigert A, Metzeler KH, Fenaux P, Medyouf H, Platzbecker U, Ades L. Efficacy and Safety of Bemcentinib in Patients With Advanced Myelodysplastic Neoplasms or Acute Myeloid Leukemia Failing Hypomethylating Agents- The EMSCO Phase II BERGAMO Trial. Leukemia. 2023. Nov;37(11):2309-2313. PMID: 37735558;
Kubasch AS, Giagounidis A, Metzgeroth G, Jonasova A, Herbst R, Diaz JMT, De Renzis B, Götze KS, Huetter-Kroenke ML, Gourin MP, Slama B, Dimicoli-Salazar S, Cony-Makhoul P, Laribi K, Park S, Jersemann K, Schipp D, Metzeler KH, Tiebel O, Sockel K, Gloaguen S, Mies A, Chermat F, Thiede C, Sapena R, Schlenk RF, Fenaux P, Platzbecker U, Adès L. Prospective Validation of a Biomarker-Driven Response Prediction Model to Romiplostim in Lower-Risk Myelodysplastic Syndromes – Results of the EUROPE Trial by EMSCO. Leukemia. 2022Oct;36(10):2519-2527. PMID: 36071100
Oeser A*, Kubasch AS*, Meschke T, Schmierer L, Grieb N, Platzbecker U, Neumuth T. “KAIT – Knowledge-based and AI-assisted platform for therapy decision support in hematology (Whitepaper)”. University of Leipzig – Innovation Center Computer Assisted Surgery. 2021. ISBN: 978-3-9822619-4-2 *shared first authorship
Kubasch AS, Kisro J, Heßling J, Schulz H, Hurtz HJ, Klausmann M, Ehrnsperger A, Willy C, Platzbecker U. Disease management of patients with immune thrombocytopenia-results of a representative retrospective survey in Germany. Ann Hematol. 2020 Sep;99(9):2085-2093. PMID: 32710167;
Kubasch AS, Schulze F, Giagounidis A, Götze KS, Krönke J, Sockel K, Middeke JM, Chermat F, Gloaguen S, Puttrich M, Weigt C, William D, Fenaux P, Schlenk RF, Thiede C, Stasik S, Mies A, Adès L, Oelschlägel U, Platzbecker U. Single agent talacotuzumab demonstrates limited efficacy but considerable toxicity in elderly high-risk MDS or AML patients failing hypomethylating agents. Leukemia. 2020 Apr;34(4):1182-1186. PMID: 31796915
Kubasch AS, Wehner R, Bazzurri S, Tunger A, Stasik S, Garzarolli M, Meinel J, Baretton G, Meier F, Thiede C, Schmitz M, Platzbecker U. Clinical, molecular, and immunological responses to pembrolizumab treatment of synchronous melanoma and acute myeloid leukemia. Blood Adv. 2018 Jun 12;2(11):1187-1190. PMID: 29844203
| 2024 | Sheba Medical Center/ ARC Innovation Center: Kubasch AS: CYNERGY – Setting Up New Methods for Long-Term Monitoring and Prediction of Immune-Related Adverse Events in Patients with Hemato-Oncological Malignancies Receiving Cellular Therapies |
| 2023 | Hefner S, Oeser A, Klötzer C, Herling C, Jentzsch M, Vucinic V, Henschler R, Platzbecker U, Kubasch AS,
MDS-337 HeMonitor: Machine Learning-Based Noninvasive Estimation of Hemoglobin (Hb) Value in Patients With Hematological Malignancies, Clinical Lymphoma Myeloma and Leukemia, Volume 23, Supplement 1, 2023, Pages S361-S362, |
| 2021 | Session: 803. Emerging Diagnostic Tools and Techniques:
Kubasch AS, Grieb N, Oeser A, Neumuth T, Yomade O, Hochhaus A, Platzbecker U, Merz M. Title: Predicting Early Relapse for Patients with Multiple Myeloma through Machine Learning The American Society of Hematology (ASH) Annual Meeting 2021, December 11-14, 2021, Atlanta, Georgia, USA |
| 2021 | Kubasch AS. Title: Common artificial intelligence projects in MDS
8th Annual European Myelodysplastic Syndromes Cooperative Group (EMSCO) Meeting, November 5, 2021 |
| 2021 | Kubasch AS, Oeser A, Grieb N, Meschke T, Nenoff K, Schmierer L, Weigert A, Gloaguen S, Sockel K, Metzeler K, Neumuth T, Platzbecker U
Title: ep575 – Towards explainable AI applications: Development of a semantic and causal model for personalized treatment decision making in myelodysplastic syndromes Jahrestagung der Deutschen, Österreichischen und Schweizerischen Gesellschaften für Hämatologie und Medizinische Onkologie (DGHO), Oktober 1-4, 2021, Berlin Abstract 575; DOI: 10.1159/000510995, |
| 2021 | Kubasch AS, Oeser A, Grieb N, Meschke T, Nenoff K, Schmierer L, Weigert A, Gloaguen S, Sockel K, Metzeler K, Neumuth T, Platzbecker U
Title: Moving Closer Towards Explainable AI Applications: Development of a Semantiv and Causal Model For Personalized Treatment Decision Making in Myelodysplastic Syndromes 16th International Congress on Myelodysplastic Syndromes, September 23–26, 2021, Virtual Congress Session: P46 / #171 Topic: AS06-Prognosis / AS06b-Predictive factors of response to treatment |
| 2021 | Kubasch AS, Title: Künstliche Intelligenz in der Medizin – Fakt oder Fiktion?
10. Sächsisches Hämatologicum, Juli 2021, Leipzig |
Contact
Dr. med. Anne Sophie Kubasch
Junior Research Group Leader “Smart Home Care” at EKFZ for Digital Health,
TUD Dresden University of Technology, Faculty of Medicine Carl Gustav Carus
Postdoctoral Research Associate in Digital Health, Economics & Policy at Hasso Plattner Institute
Postdoctoral Research Associate in Digital Health, Economics & Policy at Hasso Plattner Institute
Get involved
We warmly welcome students, researchers, healthcare professionals, and industry innovators to collaborate with us in advancing the mission of “Smart Home Care.” Opportunities include participation in collaborative projects, engagement in educational programs, and involvement in initiatives that drive innovation in healthcare.
In addition, we offer supervision for doctoral, master’s, and bachelor’s theses in areas related to digital health, Hospital-at-Home models, and patient-centered healthcare solutions.
In cooperation with Humboldt Prof. Ariel Dora Stern
Hasso Plattner Institute
Research Group Digital Health, Economics & Policy